5α-Reductase Inhibitors

Overview

4.7 out of 5 (634 Reviews)

Credits

1.00

Post Assessment Questions

5

Start Date

1 Sep 2023

Last Review Date

8 Jun 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


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Activity Description

5α-reductase inhibitors (5-ARIs), including finasteride and dutasteride, are approved by the U.S. Food and Drug Administration for treating benign prostatic hyperplasia and androgenic alopecia. These medications inhibit the enzyme 5α-reductase, reducing the conversion of testosterone into dihydrotestosterone, a hormone implicated in prostate enlargement and hair loss. This educational activity discusses the indications, mechanism of action, potential adverse events, and contraindications associated with 5-ARIs. The activity also covers off-label uses, appropriate dosing recommendations, and monitoring strategies to mitigate drug interactions and ensure patient safety.

A significant focus is placed on the influence of 5-ARIs on prostate-specific antigen levels and the requisite prostate cancer screening protocols before initiating therapy. Through this activity, healthcare professionals gain knowledge vital for optimizing treatment outcomes for patients with conditions like benign prostatic hyperplasia, prostatic bleeding, and alopecia. The goal is to equip healthcare providers with the necessary knowledge to manage these conditions while adhering to safety protocols effectively.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify appropriate indications for 5α-reductase inhibitors, such as finasteride and dutasteride, in managing benign prostatic hyperplasia and androgenic alopecia.

  • Implement standardized protocols for monitoring prostate-specific antigen levels and conducting prostate cancer screening before prescribing 5α-reductase inhibitors.

  • Apply appropriate dosing recommendations for finasteride and dutasteride based on the indications and patient characteristics.

  • Implement strategies with healthcare team members to coordinate comprehensive care for patients receiving 5-ARIs by addressing urological and dermatological concerns.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

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In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

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Reviews

Deborah Z. on 1/9/2021

Amber A. on 2/22/2021

Joseph S. on 5/9/2021

good review

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navdeepa c. on 3/20/2021

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on 2/21/2022

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Paul H. on 5/4/2022

Will continue to use the product

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Well done

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Donald S. on 1/2/2023

Good activity

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Thank you

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https://blog.culturewise.com/hs-fs/hubfs/generation%20gap.jpg?width=600&name=generation%20gap.jpg

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Natasha M. on 6/4/2023

can you stop asking same questions each time.

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Excellent

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I enjoyed the concise concrete approach to learning - very well done

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Thank you

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How does the PSA reduction differ in the hair loss dosage of 1 mg finasteride daily versus the BPH dosage of 5 mg daily?

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