Tricyclic Antidepressant Toxicity

Overview

4.7 out of 5 (30 Reviews)

Credits

1.50

Post Assessment Questions

12

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


 
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Activity Description

Tricyclic antidepressants (TCAs) were introduced in the late 1950s for the treatment of depression. With the advent of selective serotonin reuptake inhibitors (SSRIs) and other new antidepressants, the use of TCAs has decreased, although they are still used to treat depression that has not responded to treatment with less toxic agents. In adults, TCAs are also used for migraine headache prophylaxis, treatment of neuralgic pain, including the pain associated with Ciguatera poisoning, and obsessive-compulsive disorder. In children, TCAs have been used to treat nocturnal enuresis. Despite the current limited use of TCAs, TCA-overdose-associated hospitalizations and fatalities are on the rise. This activity reviews the evaluation and management of tricyclic antidepressant toxicity and highlights the role of interprofessional team members in collaborating to provide well-coordinated care and enhance outcomes for affected patients.


UAN: JA4008338-0000-23-4551-H01-P

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Describe the pathophysiology of tricyclic antidepressant toxicity.

  • Review the history and physical exam of a patient with tricyclic antidepressant toxicity.

  • Summarize the treatment options for tricyclic antidepressant toxicity.

  • Explain the importance of improving care coordination among interprofessional team members to improve outcomes for patients affected by tricyclic antidepressant toxicity.

Pharmacy Activity Type:
Disease/Drug Therapy Related


Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Pharmacists: StatPearls, LLC designates this activity for a maximum of 1.50 ACPE credit(s). (UAN: JA4008338-0000-23-4551-H01-P ). Pharmacists should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Thomas P. on 3/14/2021

brandi m. on 3/30/2021

Caleb P. on 7/28/2021

Jessica S. on 11/14/2021

MIA G. on 2/3/2022

Jacklyn V. on 5/26/2022

Finally some relatively straightforward questions that were pertinent.

Brian G. on 5/28/2022

Mary H. on 8/7/2022

Christine U. on 8/10/2022

Rayon S. on 11/15/2022

Nicole M. on 12/31/2022

Latoya R. on 1/25/2023

Ravi J. on 2/8/2023

Christine G. on 5/7/2023

Renford C. on 5/15/2023

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Anthony T. on 3/11/2024

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Tatiana M. on 8/7/2024

Rebecca D. on 10/29/2024

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