Allergic and Drug-Induced Interstitial Nephritis

Overview

4.8 out of 5 (88 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

12 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


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Activity Description

Drug-induced acute interstitial nephritis (DI-AIN), also called allergic acute interstitial nephritis, is the most common cause of acute interstitial nephritis (AIN) in developed countries. DI-AIN is associated with a sharp decline in renal function, often requiring dialysis, and has the potential for permanent renal insufficiency, especially if left untreated. Differentiating from other causes of acute kidney injury and discontinuing the causative medication is key to early reversibility. Renal biopsy is the definitive diagnostic test for AIN, and barring chronic changes seen on biopsy or contraindications, steroid therapy is the preferred treatment. This activity discusses the etiology, pathophysiology, clinical symptomatology, and treatment while emphasizing the interprofessional team's role in managing allergic interstitial nephritis.


UAN: JA4008338-0000-23-340-H01-P

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify potential allergic and drug-induced acute interstitial nephritis cases by recognizing varied presentations and conducting a thorough medication history review.

  • Differentiate allergic and drug-induced acute interstitial nephritis from other causes of acute kidney injury through clinical assessment, laboratory investigations, and renal biopsy if indicated.

  • Apply evidence-based guidelines for the treatment of allergic and drug-induced acute interstitial nephritis, including the judicious use of corticosteroids when indicated, weighing the potential benefits against risks.

  • Coordinate care and follow-up for patients with allergic and drug-induced acute interstitial nephritis to monitor renal function, medication adjustments, and potential long-term consequences, aiming for optimal outcomes.

Pharmacy Activity Type:
Disease/Drug Therapy Related


Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Pharmacists: StatPearls, LLC designates this activity for a maximum of 1.00 ACPE credit(s). (UAN: JA4008338-0000-23-340-H01-P ). Pharmacists should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Deborah Z. on 2/22/2021

Halyna H. on 6/1/2021

OSCAR P. on 9/13/2021

susma r. on 11/27/2021

Hardy M. on 1/25/2022

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on 2/22/2022

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Toni-Marie P. on 10/1/2022

Jenny R. on 10/23/2022

Dr.NIRMALA M. on 11/1/2022

Kriti M. on 11/21/2022

Good info

Kenneth R. on 12/7/2022

Meda H. on 1/16/2023

Amy J. on 2/6/2023

Ricardo C. on 2/25/2023

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Manuel M. on 10/29/2024

Stephen N. on 11/2/2024

P m. on 11/4/2024

Excellent review of acute interstitial nephritis! Thank you.

Louis M. on 11/19/2024

Unlimited Pharmacist CE

Stay up to date on the latest medical knowledge with 6820 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 8101.5 hours of CE.

Single Activity

Take this single activity

$29 1 activity

6 Month Unlimited Pharmacist CE

Access to all the Unlimited Pharmacist CE activities in all specialties.

$89 per half year per user

1 Year Unlimited Pharmacist CE

Access to all the Unlimited Pharmacist CE activities in all specialties.

$139 per 1 year per user