Antifungal Ergosterol Synthesis Inhibitors

Overview

4.7 out of 5 (16 Reviews)

Credits

1.50

Pharmacology Credits

1.50

Post Assessment Questions

9

Start Date

1 Sep 2023

Last Review Date

1 Mar 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


Unlimited Nurse Practitioner CE

Stay up to date on the latest medical knowledge with 6819 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 8103.5 hours of CE.

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Activity Description

This activity delves into the pharmacological intricacies of antifungal ergosterol synthesis inhibitors, commonly called "azoles." These medications, encompassing miconazole, ketoconazole, fluconazole, itraconazole, voriconazole, posaconazole, isavuconazole, and oteseconazole, play a crucial role in managing diverse fungal infections. The primary mechanism of action involves the inhibition of ergosterol biosynthesis, leading to the disruption of fungal cell membrane integrity. Exploring these azole antifungal agents involves covering indications, contraindications, drug interactions, and adverse event profiles. Notably, the potential for hepatotoxicity necessitates vigilant monitoring and interprofessional communication. These agents' scientific and medical examination includes in-depth discussions on pharmacokinetics, monitoring protocols, clinical toxicology, and elucidating significant box warnings.

By imparting insights into absorption, distribution, metabolism, and elimination, healthcare professionals will be equipped to make informed decisions, ensuring optimal patient outcomes. The emphasis on adverse drug reactions, such as QT interval prolongation and hepatotoxicity, along with a thorough exploration of contraindications, empowers clinicians with the knowledge essential for safe prescribing practices, ultimately enhancing collaborative patient care.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the mechanism of action of azole antifungal drugs.

  • Identify the potential adverse effects of the azole antifungal drugs.

  • Select the necessary patient monitoring when prescribing azole antifungal drugs.

  • Implement effective collaboration and communication among interprofessional team members to improve outcomes and treatment efficacy for patients who might benefit from azole therapy.

  • Outline the indications of Antifungal Ergosterol Synthesis Inhibitors

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurse Practitioners: StatPearls designates this activity for 1.50 ANCC contact hour(s), which includes 1.50 hour(s) of pharmacology. NPs should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Laura C. on 7/10/2021

Kelly S. on 12/27/2021

ALAN L. on 3/5/2022

Constance J. on 12/11/2022

Stacie C. on 6/15/2023

clinton m. on 6/21/2023

Christine G. on 8/22/2023

Anna C. on 12/31/2023

Belmari R. on 1/4/2024

Mary M. on 2/20/2024

Alan S. on 3/21/2024

Elizabeth F. on 5/21/2024

Arlene S. on 6/5/2024

JOEL C. on 8/23/2024

Lesly P. on 9/20/2024

Nicole H. on 12/16/2024

Unlimited Nurse Practitioner CE

Stay up to date on the latest medical knowledge with 6819 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 8103.5 hours of CE.

Single Activity

Take this single activity

$73.50 1 activity

6 Month Unlimited Nurse Practitioner CE

Access to all the Unlimited Nurse Practitioner CE activities in all specialties.

$299 per half year per user

1 Year Unlimited Nurse Practitioner CE

Access to all the Unlimited Nurse Practitioner CE activities in all specialties.

$479 per 1 year per user