Vincristine

Overview

4.6 out of 5 (18 Reviews)

Credits

1.50

Post Assessment Questions

11

Start Date

1 Sep 2023

Last Review Date

30 Oct 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


 
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Activity Description

Vincristine is a chemotherapy medication used to treat various types of cancer, including leukemia, lymphoma, neuroblastoma, and Wilms tumor. Vincristine belongs to the category of vinca alkaloids, a class of drugs that function by impeding the proper division of cancer cells. This drug inhibits cell growth by disrupting mitosis by interfering with microtubule polymerization. Vincristine is also utilized off-label for central nervous system (CNS) tumors, Ewing sarcoma, gestational trophoblastic tumors, multiple myeloma, ovarian cancer, primary CNS lymphoma, small cell lung cancer, and advanced thymoma in adult patients. This therapeutic review evaluates vincristine's role in diverse cancer treatment protocols, including combination therapies. This activity identifies common and rare adverse effects of vincristine while developing strategies for managing and minimizing toxicities associated with the drug. This activity considers long-term outcomes of patients, encompassing disease remission, survival rates, and quality of life. The aim is to equip healthcare professionals with the requisite knowledge and skills for ensuring the safe and effective care of patients receiving vincristine, ultimately contributing to enhanced patient outcomes within the field of oncology practice.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Apply an evidence-based approach to vincristine treatment by continuously updating clinical knowledge and practices to align with the latest guidelines and research findings.

  • Evaluate the cellular and molecular mechanisms by which vincristine exerts its anticancer effects.

  • Identify the appropriate FDA-approved indications for vincristine, distinguishing between various types of cancer it is indicated to treat.

  • Coordinate care with primary care providers, nurses, pharmacists, and oncologists to enhance awareness of monitoring parameters and potential adverse events associated with vincristine therapy.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.50 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Christopher C. on 8/12/2021

Elizabeth E. on 6/22/2022

most of the questions surrounded the point of vincristine being a cell- cycle specific medication that works in the m phase which I am not sure is clinically relevant.

Morgan P. on 6/28/2022

Shannon j. on 7/9/2022

Theodore B. on 11/19/2022

on 12/28/2022

Jamie K. on 4/17/2023

Kelly K. on 10/6/2023

Linda G. on 12/20/2023

Great review.

Richard P. on 12/23/2023

Fariborz M. on 3/7/2024

joerg r. on 3/19/2024

Seems to rely to a large extent on the package insert. Presentation would benefit from more up-to-date information about the drug.

Lee C. on 5/9/2024

Tara G. on 5/16/2024

Stephanie H. on 5/21/2024

William K. on 8/22/2024

Juana H. on 9/4/2024

Carolyn F. on 10/27/2024

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