Acetaminophen Toxicity

Overview

4.7 out of 5 (639 Reviews)

Credits

1.50

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Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes

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Activity Description

Acetaminophen toxicity is the second most common cause of liver transplantation worldwide and the most common cause of liver transplantation in the US. It is responsible for 56,000 emergency department visits, 2,600 hospitalizations, and 500 deaths per year in the United States. Fifty percent of these are unintentional overdoses. More than 60 million Americans consume acetaminophen on a weekly basis, and many are unaware that it is contained in combined products. This activity reviews the etiology, evaluation, and treatment of acetaminophen overdose and highlights the importance of the interprofessional team in both managing and preventing this problem.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

Review the pathophysiology of acetaminophen toxicity.
Describe the four clinical stages of acetaminophen toxicity.
Identify the treatment strategies for an alert patient who presents within an hour of overdose versus a patient who presents after two hours.
Explain interprofessional team strategies for educating patients about acetaminophen toxicity with the goal of preventing overdose.

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StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

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Authors: Suneil Agrawal
Editors: Babak Khazaeni
Editor-in-Chief: Brian P. Murray
Nurse Reviewer: Sandra Coleman
Pharmacy Reviewer: Mark V. Pellegrini

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In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

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This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

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Reviews

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Harry A. on 9/26/2021

i really appreciated this lesson and now appreciate the teaching style of this course!! Thank you!

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on 2/10/2022

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Vert good

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I would add the Rumack-Mathew Nomogram and explain based on it where low risk, high risk and in between means

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Thank you!

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thank you

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excellent tutorial

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Keep up the good work

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Excellent

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abim website

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Unlimited Nurse CE

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