Acetaminophen Toxicity

Overview

4.7 out of 5 (623 Reviews)

Credits

1.50

Post Assessment Questions

9

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


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Activity Description

Acetaminophen toxicity is the second most common cause of liver transplantation worldwide and the most common cause of liver transplantation in the US. It is responsible for 56,000 emergency department visits, 2,600 hospitalizations, and 500 deaths per year in the United States. Fifty percent of these are unintentional overdoses. More than 60 million Americans consume acetaminophen on a weekly basis, and many are unaware that it is contained in combined products. This activity reviews the etiology, evaluation, and treatment of acetaminophen overdose and highlights the importance of the interprofessional team in both managing and preventing this problem.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Review the pathophysiology of acetaminophen toxicity.
  • Describe the four clinical stages of acetaminophen toxicity.
  • Identify the treatment strategies for an alert patient who presents within an hour of overdose versus a patient who presents after two hours.
  • Explain interprofessional team strategies for educating patients about acetaminophen toxicity with the goal of preventing overdose.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.50 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

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  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

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Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Deborah Z. on 1/3/2021

Chinye O. on 3/15/2021

Sabrina C. on 2/26/2021

Mark C. on 6/14/2021

Lisa R. on 7/4/2021

Victoria C. on 9/4/2021

Larry M. on 7/14/2021

Michele C. on 8/8/2021

Lisa S. on 8/13/2021

Michelle W. on 8/19/2021

Patricia M. on 8/19/2021

Janet S. on 8/25/2021

Thiago C. on 8/30/2021

Vektra C. on 8/30/2021

sharon s. on 9/6/2021

Harry A. on 9/26/2021

i really appreciated this lesson and now appreciate the teaching style of this course!! Thank you!

lee a. on 10/1/2021

Hurline S. on 10/5/2021

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Patrick G. on 10/14/2021

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on 2/10/2022

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Vert good

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Laura p. on 2/5/2023

I would add the Rumack-Mathew Nomogram and explain based on it where low risk, high risk and in between means

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arvind b. on 12/25/2023

Thank you!

Michelle W. on 12/25/2023

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thank you

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ROXANNA R. on 2/22/2024

excellent tutorial

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JEANNETTE A. on 3/24/2024

Keep up the good work

Thomas S. on 3/24/2024

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Excellent

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abim website

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