Resistant Hypercalcemia
Hypercalcemia is a serum calcium (Ca) level over two standard deviations above the average mean values.
Familial Hypocalciuric Hypercalcemia
Familial hypocalciuric hypercalcemia (FHH) is a genetic condition characterized by mild hypercalcemia, typically found in otherwise healthy and asymptomatic individuals.
Malignancy-Related Hypercalcemia
More than 90% of hypercalcemia cases are caused by primary hyperparathyroidism (PHPT) or malignancy-induced hypercalcemia, with malignancy being the most common cause of hypercalcemia in hospitalized patients.
Milk-Alkali Syndrome
Milk-alkali syndrome now accounts for more than 10% of the cases of hypercalcemia and is the third most common cause of hypercalcemia in hospitalized patients (after hyperparathyroidism and hypercalcemia of malignancy).
Calcium
Genetic mutations of CaSRs, such as those found in familial hypocalciuric hypercalcemia (FHH), can affect the sensitivity of the receptors to serum calcium levels, resulting in hypo- or hypercalcemia.
Calcitriol
Hypercalcemia is the most common adverse reaction reported in at least one-third of patients taking systemic calcitriol.