The stellate ganglion forms as a result of the fusion of the inferior cervical and first thoracic sympathetic ganglions. It is present in up to 80% of the population. The stellate ganglion is an oval-shaped structure located anterior to the neck of the first rib. A thorough review of its relevant neuroanatomy is necessary for the successful and safe performance of a stellate ganglion blockade, which is useful in various clinical scenarios.
The stellate ganglion is found anterior to the neck of the first rib. It may occasionally extend to being anterior to the transverse process of the C7 cervical vertebra. It measures about 2.5 cm x1 cm x 0.5 cm in dimension. As referred to in its name it is star-shaped ("stellate" meaning star shaped). However, the shape and size of this ganglion may be variable in the population.
The stellate ganglion lies anterolateral to the longus colli muscle, medial to the scalene muscles, anterior to the transverse process and the prevertebral fascia. The ganglion is structurally separated from the posterior aspect of the cervical pleura by the suprapleural membrane. It is bounded medially by the trachea, esophagus and vertebral column.
Concerning the relevant vasculature, the vertebral vessels are anterolateral in location. The carotid artery is anterior to the ganglion. The superior intercostal artery lies laterally and the costocervical trunk of the subclavian artery branches out near the lower pole of the stellate ganglion.
The somatic branches from the stellate ganglion are the gray rami communicantes which provide sympathetic fibers to the anterior rami of the C7, C8, and T1.
The visceral branches include the inferior cardiac nerve; this is the contribution of this ganglion to the cardiac plexus in the thorax.
It gives off sympathetic nerve branches to the brachial plexus, which lies laterally, as well as tributaries to the subclavian and vertebral arteries and the brachiocephalic trunk.
Various studies have found that there may be considerable variability in the stellate ganglion across the population. Only 80% of the population has been known to have a structurally fused inferior cervical and first thoracic ganglion.
In case the inferior cervical and the first thoracic ganglion are not fused in the usual manner, then the inferior cervical ganglion is denoted as the stellate ganglion, which would usually be located anteriorly to the transverse process of the C7 cervical vertebrae.
Multiple approaches have been used to block the stellate ganglion and include the use of ultrasound, MRI and/or plain fluoroscopic guidance.
The patient is in the supine position with the head in slight extension. The head is turned towards the opposite side on which the block is to be performed. The cricoid cartilage is palpated to ascertain the C6 level. At the C6 level, we palpate for the C6 transverse process which is also known as the Chassaignac tubercle. In most individuals, the tubercle is 3 to 4cm cephalad to the sternoclavicular joint at the medial border of the sternocleidomastoid. The needle is advanced in the anteroposterior direction until it hits the tubercle. The needle is withdrawn about 2mm to come out of the longus colli muscle. A test dose of about 1 mL is administered after negative suction, then subsequently administer 8 to 10 mL of local anesthetic administration.
This technique offers the advantages of providing better bony delineation. It also involves administration of contrast which assures that the needle tip is in the appropriate fascial plane. If a striated appearance shows on the administration of the contrast media, it means that the needle tip is probably intramuscular. Immediate dissipation of the dye indicates that the needle tip is intravascular in position.
The carotid sheath and the sternocleidomastoid muscles are retracted laterally with the help of the ultrasound transducer. Gentle pressure is applied to reduce the distance between the skin and the tubercle. Needle insertion is towards the Chassaignac tubercle. The needle after contacting the tubercle is withdrawn about 1 to 2mm to bring it in the area of the prevertebral fascia. After negative aspiration, the local anesthetic (approximately 2mL) is injected, and the spread is carefully visualized with the use of the ultrasound. Once the visualization confirms subfascial drug deposition, the clinician can administer the remainder of the local anesthetic.
This method carries a slightly higher risk of pneumothorax and vertebral artery injury. However, it provides much more consistent blockade as needle lies closer to the ganglion. A smaller volume of local anesthetic can bring about a more consistent block with this technique. It is particularly useful in cases of failed blocks at the C6 level. The C7 approach always needs imaging as the C7 vertebrae have a vestigial tubercle which is not readily palpable.
Certain conditions may preclude performance of a stellate ganglion blockade. These include:
A successful stellate ganglion blockade is demonstrated by specific clinical signs which include:
These symptoms usually disappear in 4 to 6 hours after the blockade. Successful stellate ganglion blockade can be recognized clinically by the above symptoms and signs. However, the presence of Horner syndrome after a stellate ganglion block does not equate with complete blockage of the sympathetic outflow to the upper extremity. Extremity temperatures may rise by 1 to 3 degrees thereby indicating a successful block, which is the most widely employed indicator to determine the success of the stellate ganglion block. Other methods to confirm include measuring a sympathetic-galvanic response which is an increase in resistance after the block.
Complications which may arise during stellate ganglion blockade include :
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