Ace The SPEX Exam

Be prepared for the Federation of State Medical Boards® with 5,988 Questions that our experts have selected to simulate the real exam.

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About the Question Bank

Our review is designed to help you maximize your score on the SPEX Exam. StatPearls questions and articles are based on our experts review of the Federation of State Medical Boards® topics. Each review course is designed to empower you to assess your knowledge and understanding of medical principles and concepts found on the SPEX Exam.

Multiple-choice questions

We have 5,988 Multiple-choice 1st, 2nd, and 3rd order questions with four detailed teaching points linked to 3,365 PubMed indexed review articles related to the SPEX Examination. You can customize practice questions to system and clinical SPEX Student subject areas. In addition, you will have access to a pre- and post-test SPEX Exam to help you target learning and identify areas that need further study. Analytics and reports allow you to compare your scores to other students.

Achieve top scores

The StatPearls SPEX prep questions, SPEX review questions, and SPEX test questions will help you achieve a top score on the SPEX Examination. 2,711 authors and 55 editors have contributed to the development of the SPEX Exam content, which is continuously refined and updated to improve your learning experience.

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SPEX Exam Overview

  • How many hours is the SPEX Exam?

    The SPEX Exam is 6 hours.

  • How many questions is the SPEX Exam?

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SPEX Exam MCQs (5,988)

Our question bank for the SPEX Exam covers four Cognitive Difficulty Levels:

Level 1

29 Questions

Level 2

584 Questions

Level 3

4,300 Questions

Level 4

1,075 Questions

  • Allergy and Immunology - 321 questions
  • Cardiovascular - 1524 questions
  • Musculoskeletal - 1049 questions
  • Ears Nose and Throat - 314 questions
  • Endocrine and Metabolism - 729 questions
  • Ophthalmology - 253 questions
  • Gastrointestinal and Nutrition - 1295 questions
  • Renal, Urinary and Electrolytes - 670 questions
  • Human Growth and Development - 227 questions
  • Gynecologic - 246 questions
  • Hematology and Oncology - 990 questions
  • Infectious Diseases - 1577 questions
  • Skin & Subcutaneous Tissue - 586 questions
  • Nervous - 1332 questions
  • Pregnancy, Childbirth & Puerperium - 235 questions
  • Psychiatric/Behavioral & Substance Use Disorder - 508 questions
  • Pulmonary & Critical Care - 917 questions
  • Poisoning & Environmental Exposure - 960 questions
  • Biostatistics and Epidemiology - 201 questions
  • Dental - 33 questions
  • Reproductive - 58 questions
  • Sexuality and Gender - 22 questions
  • Social Sciences (Ethics/Legal/Professional) - 90 questions
  • Traumatic Injuries - 105 questions
  • Manage Care and Comply Regulations - 138 questions
  • Promote Safety and Minimize Infection - 140 questions
  • Health Promotion & Maintenance (Prevent Problems) - 362 questions
  • Basic Care and Comfort (Assist Daily Living Tasks) - 46 questions
  • Pharm/Parenteral Therapy (Drugs/Vital Signs) - 1122 questions
  • Reduction Risk (Post Procedure) - 97 questions
  • Physiological Adaptation (Care Ill Patients) - 4379 questions
  • Psychosocial (Mental Health Patient/Family) - 309 questions
  • Professional Practice - 125 questions
  • Process (Analysis, Assess, Eval, Implement, Plan) - 5432 questions
  • Caring (Hope and Support) - 41 questions
  • Communication/Documentation (Oral, Written, EMR) - 54 questions
  • Teaching/Learning (Promotes Behavior Change) - 57 questions
  • Culture/Spiritualilty (Beliefs, Practices, Ethics) - 17 questions
  • Causes - 3476 questions
  • Classification - 527 questions
  • Differential - 3432 questions
  • Evaluation Diagnostic Tests - 1803 questions
  • Evaluation Lab - 2004 questions
  • Evaluation Monitoring - 574 questions
  • Evaluation Nuclear Medicine - 19 questions
  • Evaluation Procedures - 1110 questions
  • Evaluation Radiologic - 1710 questions
  • Health Maint Prevention Public Health - 262 questions
  • History Physical - 6929 questions
  • Legal - 51 questions
  • Patient Education - 404 questions
  • Prognosis Complications - 3475 questions
  • Toxicology - 353 questions
  • Treatment Medical - 3394 questions
  • Treatment Occupation/Physical Therapy - 64 questions
  • Treatment Prehospital/EMS/Disaster - 57 questions
  • Treatment Radiation - 27 questions
  • Treatment Rehabilitation - 34 questions
  • Treatment Surgical - 724 questions
  • Healthcare Ethics - 62 questions
  • Clinical Education - 108 questions
  • Environmental - 23 questions
  • Palliative - 31 questions
  • Treatment Manipulative - 9 questions
  • Airway Management - 42 questions
  • Pain Management - 76 questions
  • Sedation and Analgesic Management - 19 questions
  • Organ and Tissue Donation - 3 questions
  • Ventilatory Management - 24 questions
  • Research and Evidence-Based Medicine - 54 questions
  • Resource Utilization - 13 questions
  • Vulnerable Populations - 67 questions
  • Therapeutics (Drug treatment) - 1701 questions
  • Biostatics and Calculations - 14 questions
  • Drug Information - 1119 questions
  • Pharmaceutics (Safely dosing medications) - 433 questions
  • Pharmacokinetics (Drug movement in body) - 226 questions

SPEX Exam Articles (3,365)

We link each review question to its peer-reviewed, PubMed-indexed article from StatPearls authors and editors.
We make it easy for you to reinforce topic areas you excel at and fill knowledge gaps with source material.