The metacarpophalangeal (MP or MCP) joint, also known as “the knuckle,” is formed by the articulation of the metacarpal head and proximal phalanx. This multiaxial joint allows flexion and extension as well as abduction and adduction motions. The MP joint also dynamically coordinates with the interphalangeal (IP) joint to perform thumb opposition and composite finger flexion. The MP joint has implications in many congenital or acquired deformities, sports-related injuries, and degenerative conditions and sequelae.
The MP joint is responsible for two planes of motion: flexion and extension, as well as abduction and adduction.
Thumb MP joint
The proximal convex surface of the first metacarpal bone is opposed by the elliptical cavity of the proximal phalanx. Additionally, two sesamoid bones secured by intersesamoid ligaments are present in the palmar aspect of the joint capsule. The first MP joint provides additional flexion to the thumb in opposition, permitting the grasping and contouring objects to facilitate fine motor tasks. Unlike the other digits of the hand, the thumb joint only has one interphalangeal joint which the MP joint coordinates thumb opposition. Compared to the other MP joints of the hand, the MP joint of the thumb has a more restricted range of motion.
Finger MP joints
The finger MP joints have an oval convex metacarpal surface that articulates with a concave, shallow proximal phalangeal surface. Despite their structural similarities, these joints are much less restricted in motion compared to the first MP joint of the thumb. Extensive musculature stabilizes these joints. On the palmar side, the flexor digitorum superficialis, flexor digitorum profundus, lumbricals, interossei, flexor digiti minimi, flexor pollicis longus, and flexor pollicis brevis muscles support the joint. Dorsally, the extensor digitorum, extensor indicis, extensor digiti minimi, extensor pollicis longus, and extensor pollicis brevis muscles reinforce the joint.
Various ligamentous structures such as the volar plate, longitudinal fibers of the joint capsule, and transverse metacarpal ligaments (superficial and deep) provide additional stability to the joint.
From deep to superficial, the anatomic structures of the MP joint facilitate the overall dynamic function of the MP joint include:
The volar plate is a short, transverse thickening of the joint capsule that functions to increase overall joint congruence and prevents MP joint hyperextension.
The joint capsule is a thin, fibrous, and durable network, reinforced by the flexor pollicis brevis and adductor pollicis brevis muscles, the palmar plate, and various collateral ligament connections. The radial and ulnar collateral ligaments arise proximally from their respective sides on the metacarpal bone, spanning the distal and volar sides of the joint to attach on the proximal phalanx. Each collateral ligament has its own proper and accessory ligamentous structures.
The volar fan-shaped accessory ligament attaches to the middle of the metacarpal head and extends to the palmar plate and deep transverse metacarpal ligament which tightens during finger extension. The dorsal, cord-shaped, proper ligament attaches to the metacarpal head and extends to the proximal phalanx base, becoming taut at about 30 degrees of finger flexion. The natatory ligament, also known as the superficial transverse metacarpal ligament, originates distal to the MP joint and runs through the webspace to insert on the proximal phalanx. It functions to resist abduction. The deep transverse metacarpal ligament connects the 2nd-5th metacarpal heads together at the volar plate and provides soft tissue support. Dorsal to this ligament, are the ribbon-shaped sagittal bands that centralize the MP joint and stabilize the extensor tendons in motion.
The MP joint forms a cavity in the mesenchyme between developing bones. The mesenchyme also gives rise to the joint capsule and other ligaments that stabilize the joint. The upper limb bud appears around the fourth week of gestation, with the development of the MP joint occurring around 6 to 7 weeks gestation. The sesamoid bones of the first metacarpophalangeal joint do not appear until approximately 12 years of age.
The primary blood supply to the hand is through the radial and ulnar arteries. The ulnar artery gives rise to the superficial palmar arch and gives off a deep branch to anastomose with the deep arch. The radial artery gives rise to the deep arch and gives off a superficial branch to anastomose with the superficial arch. This creates an extensive collateral network to prevent ischemia injury. Blood supply to the thumb MP joint may be directly the superficial arch or via a deep branch of the radial artery; the princeps pollicis artery. The arterial supply to the MP joints of the fingers is by branches from adjacent digital arteries.
The axillary lymph nodes provide lymphatic drainage of the upper limb. The lymphatic system of the upper extremity uses a pathway that originates in the distal fingers tips and palms. The lymphatic system travels on the dorsal aspect of the hand. The lymphatic vessels are typically found just posterior to the cutaneous veins. The lymph drainage continues proximally up the arm, running with the basilic vein until connecting to the lymph nodes in the lateral axillary region. 
The MP joint receives innervation from the articular branches of the dorsal and palmar digital nerves. The second to fifth MP joints receive innervation from a deep branch of the ulnar nerve that is superficial to the interosseous muscles, but deep and radial to the flexor tendon.
There are several muscles balancing the actions of the MP joint. The extrinsic and intrinsic hand muscles function in flexion and extension respectively. The intrinsic muscles acting on the MP joint include the abductor pollicis brevis, adductor pollicis, dorsal interosseus, palmar interosseus, flexor digiti minimi, flexor pollicis brevis, and lumbrical muscles. The flexor digitorum profundus, flexor digitorum superficialis, flexor pollicis longus, extensor digitorum communis, extensor indicis proprius, and extensor digiti minimi are the extrinsic muscles acting on the MP joint.
The flexor digitorum superficialis and flexor digitorum profundus muscles are the flexors of the MP joint. The flexor digitorum superficialis muscle produces more torque at the metacarpophalangeal joint than the flexor digitorum profundus muscle. Compared to the flexor digitorum profundus, the flexor digitorum superficialis muscle crosses fewer joints and is less likely to lose tension as it shortens. The flexor pollicis brevis flexes the thumb MP joint. The flexor digiti minimi muscle flexes the MP joint of the little finger.
The dorsal interosseous muscles function primarily in MP joint abduction. The abductor pollicis brevis and abductor digiti minimi muscles perform similar functions at the thumb and pinky respectively. The palmar interosseous muscles perform adduction of the MP joint to close spread fingers. The lumbrical muscles are intrinsic muscles that are weak metacarpophalangeal flexors which simultaneously extend the IP joints.
Thumb extension at the MP joint is a function of the extensor pollicis brevis and extensor pollicis longus muscles. Extension of the MP joint of digits 2-5 is a function of the extensor digitorum communis, extensor indicis, and extensor digiti minimi.Specifically, the extensor indicis and extensor digiti minimi muscles extend the MP joints at the index and little fingers respectively. The extensor digitorum communis muscle creates tension over the sagittal bands and pulls them over the proximal phalanx, to create MP joint hyperextension.
The literature describes anatomic variation regarding the location of the sesamoid bones of the MP joint. In addition to the thumb MP joint, sesamoid bones are sometimes present at the metacarpal heads of the index and little fingers.
MP Joint Arthritis
MP joint arthritis is a frequent topic in the literature discussing various conditions that ultimately result in mild to end-stage degenerative changes and deformity that can significantly impact a patient's ability to perform essential daily functions. In milder forms of acquired (e.g., post-traumatic) or degenerative arthritis and deformity, nonoperative measures are the standard, first-line treatment options:
Additionally, the healthcare provider should consider the underlying etiology as this may indicate additional management options. For example, patients with underlying rheumatoid arthritis should obtain a referral to a rheumatologist for specialized medical management to consider starting the patient on disease-modifying antirheumatic drugs (DMARDs).
Persistent symptoms, synovitis, or swelling despite a 3- to 6-month course of nonoperative interventions warrants consultation with a hand specialist for possible surgical considerations. Considerations for surgery, especially in patients with RA, require a comprehensive evaluation of the patient’s overall health and nutritional status, comorbidities, pharmacologic disease control, and infection risk. Additionally, the degree of bone deformity, which includes an assessment of total bone loss, will help to determine, which the most viable surgical options for the patient.
Metacarpophalangeal Joint Arthroscopy
Metacarpophalangeal joint arthroscopy was first described in 1979, although in general, its use remains limited.
Metacarpophalangeal Joint Arthroplasty
The primary indication for MP joint arthroplasty is severe degenerative arthritis, but the technique also can be used to treat joint deformations from multiple dislocations, subluxations, or cartilage damage.
MP joint arthroplasty remains a relatively reliable procedure in terms of its ability to restore function, reduce pain, and improve both function and range of motion. This procedure essentially involves replacement of the deformed joint with a hinged silicon implant, or newer-generation, unconstrained implants designed with either pyrocarbon or metal on polyethylene (MoP), are thought to be most likely to produce good long-term results in patients with pre-existing soft-tissue stability. In patients with end-stage degenerative deformities including compromise of the surrounding soft tissue stabilizing structures, the silicone implants are the favored option. The pyrolytic carbon joint replacements appear to be preferable for patients with well-controlled osteoarthritis or early RA with no or minimal deformity. The procedure begins with a dorsal incision at the metacarpal neck.
The extensor tendons are retracted to expose the joint capsule. The sagittal band and collateral ligaments are released followed by the joint capsule. The metacarpal head is resected and prepared for implantation of the prosthesis. Following insertion, the joint capsule is closed. The patient then is advised to remain in a splint for 12 weeks and start physical therapy at week 6 post-op. 
Metacarpophalangeal Joint Arthrodesis
Metacarpophalangeal joint arthrodesis, also known as “MP joint fusion,” is commonly used to correct MP joint arthritis in the thumb. This surgical technique usually involves a dorsal incision. The extensor interval is incised longitudinally, and the dorsal capsule is split to expose the joint. Following denuding of the diseased cartilage, fixation is possible through a variety of means, including screws, plates, and wires. Adjuvant allograft or autograft bone grafting is usable in cases of severe bone loss or deformity. The patient requires immobilization for 4 to 6 weeks or until radiographic union occurs.
MP Joint Arthritis in patients with Rheumatoid Arthritis
Rheumatoid arthritis is a common autoimmune disease associated with a progressive disability caused by synovial inflammation and hyperplasia that leads to the production of autoantibodies, rheumatoid factor, and anti-citrullinated protein antibodies which attack the MP joint and cause increasing degrees of swelling, pain, and underlying cartilage and osseous destruction. Cardiopulmonary disease, psychological disorders, and musculoskeletal complications are also characteristic of this condition.
MP joint arthritis is a distinguishing feature of rheumatoid arthritis. In RA, the destruction of the MP joint connective tissue leads to an imbalance of the active and passive forces, leading to joint instability, pain, and deformity. A typical early finding of the condition is bilateral symmetric swelling of the MP joints. Pain with passive motion or squeezing of the MP joints is a sensitive test for the joint inflammation that frequently presents with this condition. MP joint dislocation is common and classically presents in the endstage as flexion and ulnar deviation, with dislocation of the joint. Surgical intervention is a patient-centered decision to consider when the deformity severely limits function.
MP Joint Dislocation
Metacarpophalangeal (MP) joint injuries and dislocations of the fingers and thumb commonly occur secondary to direct trauma and/or falls.
A patient with an MP joint dislocation will typically present with a swollen, bruised, and obviously deformed finger. The patient will be focally tender to palpation over the joint itself in addition to the limited ability to move the finger.
Dislocations are described concerning the distal osseous fragment or bone's position relative to the proximal osseous element. Dorsal dislocations are the most common presentation pattern. In addition, dislocations are further classified as simple versus complex. The former implies a successful closed reduction is achieved by applying axial traction and splinting, while the latter indicates the MP joint dislocation is irreducible by closed means.
The classic description of complex dorsal MP dislocations are:
Complex MP dislocations, by definition, require open reduction to remove the interposing structures which are impeding reduction.
For the thumb MP joint, anatomical structures that may become trapped include the volar plate, sesamoid bones, bony fracture fragments, and the flexor pollicis longus tendon.
Thumb Collateral Ligament Injury
Thumb collateral ligaments include injuries to the radial collateral ligament (rare) or ulnar collateral ligament (UCL). Thumb UCL injuries can also be described based on existing eponyms in the literature:
Patients will typically present with a swollen, discolored thumb, with pain that is exacerbated by movement in any direction. Patients may also present significant weakness of grasp, at the base of the thumb in the first webspace, and wrist pain. The mechanism of injury is commonly hyperextension of the MP joint.
Failure to repair a Stener lesion inevitably results in chronic pain, instability, deformity, weakness, and arthritis. This causes a UCL tear to be managed surgically to prevent long term disability.
Milder injuries and ligamentous sprains (without instability) are amenable to nonoperative management. A thumb spica splint may be utilized until symptoms resolve.
Sagittal Band Rupture
Sagittal band rupture is known as “boxer’s knuckle,” for its tendency to commonly affect members of the pugilist profession. This injury involves a traumatic extensor tendon rupture on the dorsal aspect of the MP joint. Sagittal band rupture often goes unrecognized because the extensor tendon can remain in its normal midline position following the injury. Symptoms range from MP joint pain and edema, due to extensor tendon dislocation. Associated injuries include capsular injury, collateral ligament sprains, and osteochondral fractures. Many acute injuries can be managed nonsurgically using extension splints. Optimal management of chronic or subacute injuries remains unclear. Surgical management involves repair or reconstruction of the radial sagittal band.
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