[1]
Gordon FH, Watkinson A, Hodgson H. Vascular malformations of the gastrointestinal tract. Best practice & research. Clinical gastroenterology. 2001 Feb:15(1):41-58
[PubMed PMID: 11355900]
[2]
Poralla T. Angiodysplasia in the renal patient: how to diagnose and how to treat? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 1998 Sep:13(9):2188-91
[PubMed PMID: 9761492]
[3]
Chong J, Tagle M, Barkin JS, Reiner DK. Small bowel push-type fiberoptic enteroscopy for patients with occult gastrointestinal bleeding or suspected small bowel pathology. The American journal of gastroenterology. 1994 Dec:89(12):2143-6
[PubMed PMID: 7977230]
[4]
Sami SS, Al-Araji SA, Ragunath K. Review article: gastrointestinal angiodysplasia - pathogenesis, diagnosis and management. Alimentary pharmacology & therapeutics. 2014 Jan:39(1):15-34. doi: 10.1111/apt.12527. Epub 2013 Oct 20
[PubMed PMID: 24138285]
[5]
Schwartz J, Rozenfeld V, Habot B. Cessation of recurrent bleeding from gastrointestinal angiodysplasia, after beta blocker treatment in a patient with hypertrophic subaortic stenosis--a case history. Angiology. 1992 Mar:43(3 Pt 1):244-8
[PubMed PMID: 1575371]
Level 3 (low-level) evidence
[6]
Pate GE, Chandavimol M, Naiman SC, Webb JG. Heyde's syndrome: a review. The Journal of heart valve disease. 2004 Sep:13(5):701-12
[PubMed PMID: 15473466]
[7]
Gola W, Lelonek M. Clinical implication of gastrointestinal bleeding in degenerative aortic stenosis: an update. Cardiology journal. 2010:17(4):330-4
[PubMed PMID: 20690087]
[8]
Foutch PG, Rex DK, Lieberman DA. Prevalence and natural history of colonic angiodysplasia among healthy asymptomatic people. The American journal of gastroenterology. 1995 Apr:90(4):564-7
[PubMed PMID: 7717311]
[9]
Dodda G, Trotman BW. Gastrointestinal angiodysplasia. Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians. 1997:8(1):16-9
[PubMed PMID: 9048468]
[10]
Foutch PG. Angiodysplasia of the gastrointestinal tract. The American journal of gastroenterology. 1993 Jun:88(6):807-18
[PubMed PMID: 8389094]
[11]
Cheng CL, Lee CS, Liu NJ, Chen PC, Chiu CT, Wu CS. Overlooked lesions at emergency endoscopy for acute nonvariceal upper gastrointestinal bleeding. Endoscopy. 2002 Jul:34(7):527-30
[PubMed PMID: 12170402]
[12]
Raju GS, Gerson L, Das A, Lewis B, American Gastroenterological Association. American Gastroenterological Association (AGA) Institute technical review on obscure gastrointestinal bleeding. Gastroenterology. 2007 Nov:133(5):1697-717
[PubMed PMID: 17983812]
[13]
Ueno S, Nakase H, Kasahara K, Uza N, Kitamura H, Inoue S, Mikami S, Matsuura M, Chiba T. Clinical features of Japanese patients with colonic angiodysplasia. Journal of gastroenterology and hepatology. 2008 Aug:23(8 Pt 2):e363-6
[PubMed PMID: 17725595]
[14]
Chalasani N, Cotsonis G, Wilcox CM. Upper gastrointestinal bleeding in patients with chronic renal failure: role of vascular ectasia. The American journal of gastroenterology. 1996 Nov:91(11):2329-32
[PubMed PMID: 8931412]
[15]
Zuckerman GR, Cornette GL, Clouse RE, Harter HR. Upper gastrointestinal bleeding in patients with chronic renal failure. Annals of internal medicine. 1985 May:102(5):588-92
[PubMed PMID: 3872616]
[16]
King RM, Pluth JR, Giuliani ER. The association of unexplained gastrointestinal bleeding with calcific aortic stenosis. The Annals of thoracic surgery. 1987 Nov:44(5):514-6
[PubMed PMID: 3499881]
[17]
Cappell MS, Lebwohl O. Cessation of recurrent bleeding from gastrointestinal angiodysplasias after aortic valve replacement. Annals of internal medicine. 1986 Jul:105(1):54-7
[PubMed PMID: 3487267]
[18]
Vincentelli A, Susen S, Le Tourneau T, Six I, Fabre O, Juthier F, Bauters A, Decoene C, Goudemand J, Prat A, Jude B. Acquired von Willebrand syndrome in aortic stenosis. The New England journal of medicine. 2003 Jul 24:349(4):343-9
[PubMed PMID: 12878741]
[19]
Marie I, Ducrotte P, Antonietti M, Herve S, Levesque H. Watermelon stomach in systemic sclerosis: its incidence and management. Alimentary pharmacology & therapeutics. 2008 Aug 15:28(4):412-21. doi: 10.1111/j.1365-2036.2008.03739.x. Epub 2008 May 21
[PubMed PMID: 18498445]
[20]
Demirozu ZT, Radovancevic R, Hochman LF, Gregoric ID, Letsou GV, Kar B, Bogaev RC, Frazier OH. Arteriovenous malformation and gastrointestinal bleeding in patients with the HeartMate II left ventricular assist device. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 2011 Aug:30(8):849-53. doi: 10.1016/j.healun.2011.03.008. Epub 2011 Apr 29
[PubMed PMID: 21530318]
[21]
Kushnir VM, Sharma S, Ewald GA, Seccombe J, Novak E, Wang IW, Joseph SM, Gyawali CP. Evaluation of GI bleeding after implantation of left ventricular assist device. Gastrointestinal endoscopy. 2012 May:75(5):973-9. doi: 10.1016/j.gie.2011.12.014. Epub 2012 Feb 15
[PubMed PMID: 22341716]
[22]
Brock AS, Cook JL, Ranney N, Rockey DC. Clinical problem-solving. A not-so-obscure cause of gastrointestinal bleeding. The New England journal of medicine. 2015 Feb 5:372(6):556-61. doi: 10.1056/NEJMcps1302223. Epub
[PubMed PMID: 25651250]
[23]
Singh G, Albeldawi M, Kalra SS, Mehta PP, Lopez R, Vargo JJ. Features of patients with gastrointestinal bleeding after implantation of ventricular assist devices. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2015 Jan:13(1):107-14.e1. doi: 10.1016/j.cgh.2014.05.012. Epub 2014 May 21
[PubMed PMID: 24858705]
[24]
Ghdes O, Gaja A, Blel A, Jarraya H, Mnif N. Ileal angiodysplasia presentation as a bowel obstruction: A case report. International journal of surgery case reports. 2017:39():301-304. doi: 10.1016/j.ijscr.2017.06.068. Epub 2017 Jul 24
[PubMed PMID: 28892784]
Level 3 (low-level) evidence
[25]
Chen HM, Ge ZZ, Liu WZ, Lu H, Xu CH, Fang JY, Xiao SD. [The mechanisms of thalidomide in treatment of angiodysplasia due to hypoxia]. Zhonghua nei ke za zhi. 2009 Apr:48(4):295-8
[PubMed PMID: 19576118]
[26]
Fujita H, Momoi M, Chuganji Y, Tomiyama J. Increased plasma vascular endothelial growth factor levels in patients with angiodysplasia. Journal of internal medicine. 2000 Sep:248(3):268-9
[PubMed PMID: 10971796]
[27]
Starke RD, Ferraro F, Paschalaki KE, Dryden NH, McKinnon TA, Sutton RE, Payne EM, Haskard DO, Hughes AD, Cutler DF, Laffan MA, Randi AM. Endothelial von Willebrand factor regulates angiogenesis. Blood. 2011 Jan 20:117(3):1071-80. doi: 10.1182/blood-2010-01-264507. Epub 2010 Nov 3
[PubMed PMID: 21048155]
[28]
Mudhar HS, Balsitis M. Colonic angiodysplasia and true diverticula: is there an association? Histopathology. 2005 Jan:46(1):81-8
[PubMed PMID: 15656890]
[29]
Boley SJ, DiBiase A, Brandt LJ, Sammartano RJ. Lower intestinal bleeding in the elderly. American journal of surgery. 1979 Jan:137(1):57-64
[PubMed PMID: 310250]
[30]
Rodrigues JP, Chivia J, Figueiredo PC. Fleeting Angiodysplasia. GE Portuguese journal of gastroenterology. 2018 Jun:25(4):203-204. doi: 10.1159/000481176. Epub 2017 Oct 7
[PubMed PMID: 29998169]
[31]
Richter JM, Hedberg SE, Athanasoulis CA, Schapiro RH. Angiodysplasia. Clinical presentation and colonoscopic diagnosis. Digestive diseases and sciences. 1984 Jun:29(6):481-5
[PubMed PMID: 6609803]
[32]
Dusold R, Burke K, Carpentier W, Dyck WP. The accuracy of technetium-99m-labeled red cell scintigraphy in localizing gastrointestinal bleeding. The American journal of gastroenterology. 1994 Mar:89(3):345-8
[PubMed PMID: 8122642]
[33]
Kuhle WG, Sheiman RG. Detection of active colonic hemorrhage with use of helical CT: findings in a swine model. Radiology. 2003 Sep:228(3):743-52
[PubMed PMID: 12954894]
[34]
Walker TG. Acute gastrointestinal hemorrhage. Techniques in vascular and interventional radiology. 2009 Jun:12(2):80-91. doi: 10.1053/j.tvir.2009.08.002. Epub
[PubMed PMID: 19853226]
[35]
Ress AM, Benacci JC, Sarr MG. Efficacy of intraoperative enteroscopy in diagnosis and prevention of recurrent, occult gastrointestinal bleeding. American journal of surgery. 1992 Jan:163(1):94-8; discussion 98-9
[PubMed PMID: 1733380]
[36]
Raju GS, Gerson L, Das A, Lewis B, American Gastroenterological Association. American Gastroenterological Association (AGA) Institute medical position statement on obscure gastrointestinal bleeding. Gastroenterology. 2007 Nov:133(5):1694-6
[PubMed PMID: 17983811]
[37]
Vargo JJ. Clinical applications of the argon plasma coagulator. Gastrointestinal endoscopy. 2004 Jan:59(1):81-8
[PubMed PMID: 14722558]
[38]
Ladas SD, Karamanolis G, Ben-Soussan E. Colonic gas explosion during therapeutic colonoscopy with electrocautery. World journal of gastroenterology. 2007 Oct 28:13(40):5295-8
[PubMed PMID: 17879396]
[39]
Ertekin C, Taviloglu K, Barbaros U, Guloglu R, Dolay K. Endoscopic band ligation: alternative treatment method in nonvariceal upper gastrointestinal hemorrhage. Journal of laparoendoscopic & advanced surgical techniques. Part A. 2002 Feb:12(1):41-5
[PubMed PMID: 11905861]
[40]
Kobeissy A, Mallat M, Jamali F, Yaghi S, Jabbour M, Shabb N, Soweid A. Endoscopic removal of a bleeding colonic polypoid angiodysplasia: case report. Acta gastro-enterologica Belgica. 2010 Jul-Sep:73(3):406-8
[PubMed PMID: 21086949]
Level 3 (low-level) evidence
[41]
Selinger RR, McDonald GB, Hockenbery DM, Steinbach G, Kimmey MB. Efficacy of neodymium:YAG laser therapy for gastric antral vascular ectasia (GAVE) following hematopoietic cell transplant. Bone marrow transplantation. 2006 Jan:37(2):191-7
[PubMed PMID: 16284614]
[42]
Weldon DT, Burke SJ, Sun S, Mimura H, Golzarian J. Interventional management of lower gastrointestinal bleeding. European radiology. 2008 May:18(5):857-67. doi: 10.1007/s00330-007-0844-2. Epub 2008 Jan 8
[PubMed PMID: 18185932]
[43]
Mirsadraee S, Tirukonda P, Nicholson A, Everett SM, McPherson SJ. Embolization for non-variceal upper gastrointestinal tract haemorrhage: a systematic review. Clinical radiology. 2011 Jun:66(6):500-9. doi: 10.1016/j.crad.2010.11.016. Epub 2011 Mar 2
[PubMed PMID: 21371695]
Level 1 (high-level) evidence
[44]
Neuman HB, Zarzaur BL, Meyer AA, Cairns BA, Rich PB. Superselective catheterization and embolization as first-line therapy for lower gastrointestinal bleeding. The American surgeon. 2005 Jul:71(7):539-44; discussion 544-5
[PubMed PMID: 16089115]
[45]
DeBarros J, Rosas L, Cohen J, Vignati P, Sardella W, Hallisey M. The changing paradigm for the treatment of colonic hemorrhage: superselective angiographic embolization. Diseases of the colon and rectum. 2002 Jun:45(6):802-8
[PubMed PMID: 12072634]
[46]
Czymek R, Kempf A, Roblick UJ, Bader FG, Habermann J, Kujath P, Bruch HP, Fischer F. Surgical treatment concepts for acute lower gastrointestinal bleeding. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2008 Dec:12(12):2212-20. doi: 10.1007/s11605-008-0597-5. Epub 2008 Jul 18
[PubMed PMID: 18636299]
[47]
Marlu R, Barthelon J, Durand A, Mathieu N, Barro C, Granger V, Tatu A, Pernod G, Polack B, Bonaz B. Long-term therapy with bevacizumab in a patient with Glanzmann's thrombasthenia and recurrent digestive bleeding due to gastrointestinal angiodysplastic lesions. The American journal of gastroenterology. 2015 Feb:110(2):352-3. doi: 10.1038/ajg.2014.391. Epub
[PubMed PMID: 25646919]
[48]
Ge ZZ, Chen HM, Gao YJ, Liu WZ, Xu CH, Tan HH, Chen HY, Wei W, Fang JY, Xiao SD. Efficacy of thalidomide for refractory gastrointestinal bleeding from vascular malformation. Gastroenterology. 2011 Nov:141(5):1629-37.e1-4. doi: 10.1053/j.gastro.2011.07.018. Epub 2011 Jul 22
[PubMed PMID: 21784047]
[49]
Barkin JS, Ross BS. Medical therapy for chronic gastrointestinal bleeding of obscure origin. The American journal of gastroenterology. 1998 Aug:93(8):1250-4
[PubMed PMID: 9707046]
[50]
Junquera F, Feu F, Papo M, Videla S, Armengol JR, Bordas JM, Saperas E, Piqué JM, Malagelada JR. A multicenter, randomized, clinical trial of hormonal therapy in the prevention of rebleeding from gastrointestinal angiodysplasia. Gastroenterology. 2001 Nov:121(5):1073-9
[PubMed PMID: 11677198]
Level 1 (high-level) evidence
[51]
Szilagyi A, Ghali MP. Pharmacological therapy of vascular malformations of the gastrointestinal tract. Canadian journal of gastroenterology = Journal canadien de gastroenterologie. 2006 Mar:20(3):171-8
[PubMed PMID: 16550261]
[52]
Brown C, Subramanian V, Wilcox CM, Peter S. Somatostatin analogues in the treatment of recurrent bleeding from gastrointestinal vascular malformations: an overview and systematic review of prospective observational studies. Digestive diseases and sciences. 2010 Aug:55(8):2129-34. doi: 10.1007/s10620-010-1193-6. Epub
[PubMed PMID: 20393879]
Level 3 (low-level) evidence
[53]
Bon C, Aparicio T, Vincent M, Mavros M, Bejou B, Raynaud JJ, Zampeli E, Airinei G, Sautereau D, Benamouzig R, Michopoulos S. Long-acting somatostatin analogues decrease blood transfusion requirements in patients with refractory gastrointestinal bleeding associated with angiodysplasia. Alimentary pharmacology & therapeutics. 2012 Sep:36(6):587-93. doi: 10.1111/apt.12000. Epub 2012 Jul 26
[PubMed PMID: 22831465]
[54]
Nardone G, Compare D, Scarpignato C, Rocco A. Long acting release-octreotide as "rescue" therapy to control angiodysplasia bleeding: A retrospective study of 98 cases. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 2014 Aug:46(8):688-94. doi: 10.1016/j.dld.2014.04.011. Epub 2014 Jun 2
[PubMed PMID: 24893688]
Level 2 (mid-level) evidence
[55]
Strate LL. Lower GI bleeding: epidemiology and diagnosis. Gastroenterology clinics of North America. 2005 Dec:34(4):643-64
[PubMed PMID: 16303575]
[56]
Redondo-Cerezo E, Gómez-Ruiz CJ, Sánchez-Manjavacas N, Viñuelas M, Jimeno C, Pérez-Vigara G, Morillas J, Pérez-García JI, García-Cano J, Pérez-Sola A. Long-term follow-up of patients with small-bowel angiodysplasia on capsule endoscopy. Determinants of a higher clinical impact and rebleeding rate. Revista espanola de enfermedades digestivas. 2008 Apr:100(4):202-7
[PubMed PMID: 18563976]
[57]
Grooteman KV, Dalloyaux S, van den Bemt MCP, de Graaf J, Verbeek ALM, Jackson CS, van Geenen EJM, Drenth JPH. Risk factors for incidentally detected and symptomatic angiodysplasias: a case-control study with the general population as reference. European journal of gastroenterology & hepatology. 2019 Apr:31(4):458-462. doi: 10.1097/MEG.0000000000001335. Epub
[PubMed PMID: 30562184]
Level 2 (mid-level) evidence