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Which of the following breast cancers has thread-like strands of carcinoma cells, one cell thick through a fibrous matrix?
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Teaching Points
- The carcinoma cells of infiltrating lobular carcinomas are in single file groups called "Indian file" cells.
- ILC is characterized by bland, small, round cells that have scant cytoplasm. They usually infiltrate the tissue in a single file.
- Lobular cancer usually does not damage the adjacent anatomic structures or initiate a significant connective tissue response.
- Because of the distinctive biology and growth pattern and biology, lobular carcinomas is often easily diagnosed on palpation. However, Lobular carcinoma is also known to be bilateral, multicentric and multifocal, which makes breast conservation therapy unlikley.
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PubMed References
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