A 45-year-old with severe asthma undergoes a laparotomy for a bowel obstruction. Postoperatively he has minimal nausea or vomiting. Which of the following could be the reason for the antiemetic effect?
Select Your Answer:
Prednisone, which is a steroid, is not the typical antiemetic drug but there is some evidence that high doses of intravenous steroids may have an antiemetic effect.
Steroids are often given to patients with cancer to reduce nausea, but with the availability of better and safer drugs, steroid use has declined.
Best drugs for nausea include 5-HT3 receptor antagonists like ondansetron, dopamine antagonists like domperidone and NK1 receptor antagonist like casopitant.
Cannabinoids are also known to have an antiemetic effect.
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Adult Lab Normals
Pediatric Lab Normals
Point of care sonographic diagnosis of maternal small bowel obstruction complicating pregnancy., Sherer DM,Dalloul M,Schwartzman A,Strasburger A,Farrell RA,Zinn H,Abulafia O,, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2016 Jan 18 [PubMed PMID: 26775812]
Clinician-performed abdominal sonography., Dickman E,Tessaro MO,Arroyo AC,Haines LE,Marshall JP,, European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2015 Oct [PubMed PMID: 26038027]
Point-of-care ultrasonography for the diagnosis of small bowel obstruction in the emergency department., Guttman J,Stone MB,Kimberly HH,Rempell JS,, CJEM, 2015 Mar [PubMed PMID: 25927264]
Change in mechanical bowel obstruction demographic and etiological patterns during the past century: observations from one health care institution., Drożdż W,Budzyński P,, Archives of surgery (Chicago, Ill. : 1960), 2012 Feb [PubMed PMID: 22351915]
Volvulus of the small intestine., Frazee RC,Mucha P Jr,Farnell MB,van Heerden JA,, Annals of surgery, 1988 Nov [PubMed PMID: 3190283]
Small intestinal obstruction., Mucha P Jr,, The Surgical clinics of North America, 1987 Jun [PubMed PMID: 3296252]
Adult small bowel obstruction., Taylor MR,Lalani N,, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2013 Jun [PubMed PMID: 23758299]