A male with a lymphoma is treated with multiple chemotherapeutic agents. One month later, he complains of paresthesias in his legs that include numbness and tingling. Which agent would most likely cause such symptoms?
Select Your Answer:
The patient has reversible peripheral neuropathy from vincristine.
The lymphoma is being treated with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP).
Side effects of vincristine include constipation, bedwetting, increase or decrease in urination, stomach cramps, dizziness, painful urination, lack of sweating, joint pain, lightheadedness, side back or low back pain, visual changes, drooping eyelids, headache, jaw pain, difficulty controlling muscle movement, numbness or tingling in toes or fingers, orchialgia, weakness, leukopenia, thrombocytopenia, and mouth inflammation.
The peripheral neuropathy is often permanent and may present as a foot drop.
Adult Lab Normals
Pediatric Lab Normals
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