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Study of functional properties of various receptors made from coronal brain slices uses whole cell voltage clamp recordings. A holding potential of -60 mV is established. Bath application of receptor agonists for four different types consistently either elicited inhibitory or excitatory postsynaptic currents. One receptor only elicited a postsynaptic response at a holding potential of 0 mV. Which of the following is most likely to be this receptor?
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Teaching Points
- NMDA requires both an agonist and neuronal depolarization to be activated.
- NDMA is a type of glutamate receptor and is an ion channel that allows the passage of sodium and calcium ions.
- Depolarization and agonist activation allows the blockage by a magnesium ion to dislodge.
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