What most commonly causes the drug-induced form of Sweet syndrome?
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Acute febrile neutrophilic dermatosis is characterized by the sudden onset of fever; leukocytosis; and tender, red, well-demarcated plaques and papules. There are dense infiltrates of neutrophilic granulocytes.
It is also known as Sweet syndrome.
Half of the patients have a fever, two-thirds have arthralgia or arthritis, and eye involvement is seen in more than one-third. It is most often conjunctivitis or iridocyclitis. Oral aphthae are seen in 13%.
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Adult Lab Normals
Pediatric Lab Normals
Kawakami T,Ohashi S,Kawa Y,Takahama H,Ito M,Soma Y,Mizoguchi M, Elevated serum granulocyte colony-stimulating factor levels in patients with active phase of sweet syndrome and patients with active behcet disease: implication in neutrophil apoptosis dysfunction. Archives of dermatology. 2004 May [PubMed PMID: 15148101]
Jo T,Horio K,Migita K, Sweet's syndrome in patients with MDS and MEFV mutations. The New England journal of medicine. 2015 Feb 12 [PubMed PMID: 25671271]
Rochet NM,Chavan RN,Cappel MA,Wada DA,Gibson LE, Sweet syndrome: clinical presentation, associations, and response to treatment in 77 patients. Journal of the American Academy of Dermatology. 2013 Oct [PubMed PMID: 23891394]
von den Driesch P, Sweet's syndrome (acute febrile neutrophilic dermatosis) Journal of the American Academy of Dermatology. 1994 Oct [PubMed PMID: 8089280]
Nesterovitch AB,Gyorfy Z,Hoffman MD,Moore EC,Elbuluk N,Tryniszewska B,Rauch TA,Simon M,Kang S,Fisher GJ,Mikecz K,Tharp MD,Glant TT, Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6/SHP1) may contribute to neutrophilic dermatoses. The American journal of pathology. 2011 Apr [PubMed PMID: 21406173]