Which of the following is an herbal medicine that has been used to treating depression?
Select Your Answer:
St. John's wort has been shown to improve very mild depression.
Most severe cases of depression are resistant to St. John's wort.
Less than 20 percent of patients with depression respond to St. John's wort.
St. John's wort is not a replacement for standard antidepressant drugs. It is a monoamine oxidase inhibitor with multiple drug interactions. Warfarin dosages may need adjustment due to decreased effectiveness when taken concurrently with St. John's wort.
*eMedicine, Google Scholar, UpToDate, WheelessOnline, and DermNet are not affiliated with StatPearls. We do not control their content or advertising.
Adult Lab Normals
Pediatric Lab Normals
Anti-quorum sensing and anti-biofilm activities of Hypericum perforatum L. extracts against Pseudomonas aeruginosa., Doğan Ş,Gökalsın B,Şenkardeş İ,Doğan A,Cenk Sesal N,, Journal of ethnopharmacology, 2019 Feb 11 [PubMed PMID: 30763694]
In vitro antioxidant assessment, screening of enzyme inhibitory activities of methanol and water extracts and gene expression in Hypericum lydium., Eruygur N,Ucar E,Akpulat HA,Shahsavari K,Safavi SM,Kahrizi D,, Molecular biology reports, 2019 Feb 14 [PubMed PMID: 30762165]
Thidiazuron-induced plant regeneration from hypocotyl cultures of St. John's wort (Hypericum perforatum. cv 'Anthos')., Murch SJ,Choffe KL,Victor JMR,Slimmon TY,KrishnaRaj S,Saxena PK,, Plant cell reports, 2000 May [PubMed PMID: 30754820]
Tryptophan is a precursor for melatonin and serotonin biosynthesis in in vitro regenerated St. John's wort (Hypericum perforatum L. cv. Anthos) plants., Murch SJ,KrishnaRaj S,Saxena PK,, Plant cell reports, 2000 Jun [PubMed PMID: 30754808]
First Report of Pestalotiopsis microspora Causing Leaf Spot of Hidcote (Hypericum patulum) in Japan., Zhang M,Wu HY,Tsukiboshi T,Okabe I,, Plant disease, 2010 Aug [PubMed PMID: 30743469]