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A 17-year-old female complains of fatigue, joint pain, and chest pain. She is noted to have a malar rash, right knee effusion, and a cardiac friction rub. Laboratories show WBC 6,500 cells/mm3; Hemoglobin 10.5 grams/dL; platelets 250,000 cells/mm3; BUN 12 mg/dL; creatinine 0.9 mg/dL; erythrocyte sedimentation rate 72 millimeters/hour; ANA 1:640 with a nucleolar pattern. Urinalysis shows 1+ protein but is otherwise negative. A chest x-ray is normal, and an ECG shows normal sinus rhythm. Which of the following is appropriate for this patient?

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