Overview

4.6 out of 5 (26 Reviews)

Credits

1.50

Post Assessment Questions

7

Start Date

1 Jan 2021

Last Review Date

19 Feb 2024

Expiration Date

31 Dec 2023

Estimated Time To Finish

90 Minutes


 
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Activity Description

Misoprostol is exclusively approved by the US Food and Drug Administration (FDA) for the prevention and treatment of gastric ulcers induced by nonsteroidal anti-inflammatory drugs (NSAIDs) in patients who are taking NSAIDs and are at high risk for ulceration. Misoprostol has 4 primary effects, including cytoprotection of the gastrointestinal mucosa, uterotonic properties, diarrhea, and abdominal pain, with the latter 2 considered adverse effects. Misoprostol is indicated, although not FDA-approved, for short-term treatment of active duodenal or gastric ulcers caused by other factors. Despite its global use in gynecology and obstetrics, none of these applications are FDA-approved. The regulatory landscape in the United States has changed since 2022, following the overturn of Roe v. Wade, with state-to-state regulations evolving.

The combination of misoprostol and mifepristone is FDA-approved for medical abortions, offering a highly effective option with an acceptable safety profile. In instances where mifepristone is unavailable, a misoprostol-only regimen is the recommended alternative. This activity will emphasize the mechanism of action, adverse event profile, pharmacokinetics, monitoring, and relevant interactions of misoprostol, which are essential for interprofessional team members treating patients with conditions warranting its use. This activity helps clinicians gain insight into the optimal utilization of misoprostol, particularly in collaborative efforts to address gastrointestinal, obstetric, and gynecological issues.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify appropriate clinical indications for misoprostol administration, including but not limited to postpartum hemorrhage, medical abortion, and induction of labor.

  • Implement evidence-based protocols for the safe and effective use of misoprostol in clinical practice, ensuring adherence to dosing guidelines, administration routes, and monitoring parameters.

  • Apply pharmacological knowledge to optimize misoprostol dosing and administration in diverse patient populations.

  • Collaborate with other healthcare professionals to optimize patient care and treatment outcomes involving misoprostol.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.50 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

david h. on 11/28/2021

Angjelin S. on 5/3/2022

Rebecca I. on 5/12/2022

Emily G. on 5/16/2022

Natalia M. on 8/25/2022

Nicole F. on 8/29/2022

IRIS O. on 10/3/2022

Christy E. on 10/10/2022

Sherie O. on 12/1/2022

Darra H. on 1/7/2023

Dominika S. on 2/13/2023

amy s. on 2/16/2023

Elizabeth H. on 3/2/2023

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Shirley A. on 3/24/2023

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Nicole S. on 5/3/2023

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