Lambert-Eaton Myasthenic Syndrome

Overview

4.6 out of 5 (27 Reviews)

Credits

1.00

Post Assessment Questions

5

Start Date

1 Jan 2021

Last Review Date

23 Oct 2023

Expiration Date

31 Dec 2023

Estimated Time To Finish

60 Minutes


 
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Activity Description

Lambert-Eaton myasthenic syndrome (LEMS) is a neuromuscular junction disorder affecting communication between nerves and muscles. This intricate disorder can manifest due to a paraneoplastic syndrome or a primary autoimmune disorder. The majority of cases are associated with small-cell lung cancer. This activity primarily focuses on analyzing the prominent clinical symptom of muscle weakness, which is driven by the development of antibodies that target voltage-gated calcium channels on presynaptic nerve terminals. As a result, the release of the acetylcholine neurotransmitter is reduced. This activity helps gain valuable insights into the intricate pathogenesis, practical diagnostic approaches, and tailored treatment strategies for LEMS. This activity also highlights the crucial role of the interprofessional healthcare team in coordinating the comprehensive management of this intricate syndrome.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify early clinical indicators of Lambert-Eaton myasthenic syndrome, such as proximal muscle weakness and autonomic dysfunction.

  • Implement individualized symptomatic management strategies tailored to LEMS severity to optimize acetylcholine levels and neuromuscular transmission.

  • Select the most suitable treatment options for LEMS patients based on the severity of weakness and malignancy association.

  • Communicate effectively with LEMS patients and their families, explaining the diagnosis, treatment options, prognosis, and potential adverse effects and outcomes of the treatment.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.00 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Micheal M. on 12/7/2021

Dr Jagveer S. on 1/4/2023

Aseeb R. on 4/17/2023

Svetlana T. on 5/8/2023

Bernadette M. on 5/17/2023

Gaston D. on 6/11/2023

Mark L. on 6/24/2023

ASEEDU K. on 6/29/2023

asi y. on 9/8/2023

debbie s. on 10/14/2023

Marcus T. on 11/10/2023

ISLAM A. on 11/11/2023

Augusto L. on 11/13/2023

visa on 11/14/2023

Pamela P. on 11/24/2023

JAMES N. on 11/29/2023

Manish S. on 12/4/2023

Julia W. on 12/4/2023

Shreekant P. on 12/9/2023

Mohamed E. on 12/16/2023

Great review.

Richard P. on 12/17/2023

Juan M. on 12/18/2023

Richard S. on 12/21/2023

Gregorio J. on 12/29/2023

Karl O. on 2/2/2024

Bozena B. on 3/3/2024

Excellent questions and explanations

joerg r. on 3/18/2024

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