Acute Lymphocytic Leukemia

Overview

4.5 out of 5 (106 Reviews)

Credits

1.50

Post Assessment Questions

8

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


 
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Activity Description

Acute lymphocytic leukemia (ALL) is a malignancy of B or T lymphoblasts characterized by uncontrolled proliferation of abnormal, immature lymphocytes and their progenitors which ultimately leads to the replacement of bone marrow elements and other lymphoid organs resulting in a characteristic disease pattern. ALL accounts for approximately 2 percent of lymphoid neoplasms in the United States and occurs slightly more frequently in males than females and three times as frequently in Caucasians as in African Americans. Patients typically present with symptoms related to anemia, thrombocytopenia, and neutropenia due to the replacement of the bone marrow with the tumor. Symptoms can include fatigue, easy or spontaneous bruising and/or bleeding, and infections. Additionally, B-symptoms, such as fever, night sweats, and unintentional weight loss, are often present but may be mild, and hepatomegaly, splenomegaly, and lymphadenopathy can be seen in up to half of adults on presentation. Central nervous system (CNS) involvement is common and can be accompanied by cranial neuropathies or symptoms, predominantly meningeal, related to increased intracranial pressure. This activity examines when acute lymphocytic leukemia should be considered on differential diagnosis and how to properly evaluate it. This activity highlights the role of the interprofessional team in caring for patients with this condition.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the epidemiology of acute lymphocytic leukemia.

  • Outline the exam findings typically seen in patients with acute lymphocytic leukemia.

  • Review the management of acute lymphocytic leukemia.

  • Explain modalities to improve care coordination among interprofessional team members in order to improve outcomes for patients affected by acute lymphocytic leukemia.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Physicians and Physician Associates: StatPearls, LLC designates this enduring material for a maximum of 1.50 AMA PRA Category 1 Credit(s)TM. Physicians and PAs should only claim credit commensurate with the extent of their participation in the activity.

American Board of Anesthesiology: This activity contributes to the CME component of the American Board of Anesthesiology’s redesigned Maintenance of Certification in AnesthesiologyTM (MOCA®) program, known as MOCA 2.0®. Please consult the ABA website, www.theABA.org, for a list of all MOCA 2.0 requirements.

American Board of Internal Medicine: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.50 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

American Board of Pathology: Successful completion of this Continuing Certification activity, which includes participation in the evaluation component, enables the participant to earn up to 1.50 Lifelong Learning (CME) credits in the American Board of Pathology’s Continuing Certification Program.

American Board of Pediatrics: Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 1.50 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

American Board of Surgery: Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn credit toward the CME and Self-Assessment requirement(s) of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.

Royal College of Physicians and Surgeons of Canada: Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Henrik H. on 2/8/2021

ayodeji a. on 7/15/2021

Larry M. on 7/18/2021

Christopher C. on 8/1/2021

Rene W. on 8/27/2021

Amal A. on 9/4/2021

Kelli B. on 9/27/2021

MOSFER A. on 9/4/2022

Harry A. on 10/17/2021

on 12/27/2021

Tiffany N. on 2/5/2022

Timothy M. on 2/16/2022

Jennifer K. on 2/25/2022

Anne C. on 3/3/2022

Jessica B. on 3/7/2022

Tamara L. on 3/14/2022

Surabhi C. on 3/23/2022

Dr.Mallikarjun K. on 5/1/2022

Christine U. on 5/6/2022

PATIENCE A. on 5/18/2022

sherman y. on 5/30/2022

Shannon j. on 6/27/2022

Rohit A. on 7/4/2022

Amelia B. on 10/5/2022

Theodore B. on 10/25/2022

Sara M. on 10/28/2022

Stephanie K. on 11/4/2022

Dr Jagveer S. on 11/9/2022

Lindsey M. on 11/19/2022

Good info

Kenneth R. on 11/27/2022

Vektra C. on 12/26/2022

Ronald L. on 1/28/2023

Christy M. on 2/28/2023

Ahmmed A. on 3/5/2023

Robert F. on 3/7/2023

Akshaya K. on 4/4/2023

Daniel H. on 4/11/2023

Matthew N. on 4/16/2023

Alexander W. on 4/24/2023

Michael R. on 5/21/2023

cynthia s. on 6/11/2023

Adithya nikhileshwar B. on 6/13/2023

Sean K. on 6/26/2023

Ashley W. on 6/30/2023

Susan f. on 7/4/2023

Cerise M. on 7/7/2023

Kelly K. on 7/10/2023

Samantha P. on 7/26/2023

kimberly g. on 8/8/2023

Grace A. on 8/9/2023

Joshua K. on 8/19/2023

no abnormal cytogenetics are not necessarily a good prognosis since there are prognostically positive cytogenetic abnormalities.

Diana S. on 8/22/2023

Steven S. on 9/8/2023

Chris C. on 9/9/2023

Dr Sruthi G. on 9/20/2023

Essam M. on 9/18/2023

Tanya H. on 9/29/2023

Thanks

Matthew C. on 10/2/2023

Richard C. on 10/8/2023

Sushma B. on 10/13/2023

Liam M. on 10/19/2023

Karamo C. on 10/21/2023

Daniel I. on 10/24/2023

Kody S. on 10/30/2023

Nivetha V. on 11/11/2023

Donna P. on 11/15/2023

Likta N. on 12/7/2023

Great review.

Richard P. on 12/10/2023

Hawabu S. on 12/12/2023

Scott S. on 12/18/2023

Waldo F. on 12/21/2023

Information was not provided in the information about ALL to answer the initial question (with Tdt in answer) or the question with xanthine oxidase in the answer. The questions would be fine if the information were included in the educational information about ALL.

Mary S. on 12/28/2023

francisco B. on 12/28/2023

Melissa W. on 12/28/2023

Mary H. on 12/28/2023

Cherie T. on 12/28/2023

Steven L. on 12/29/2023

Meredith G. on 12/31/2023

Sushma B. on 1/3/2024

BRANDI B. on 1/5/2024

Maria N. on 1/7/2024

Lori M. on 1/23/2024

shazia z. on 1/24/2024

Ambreen S. on 1/25/2024

Vonda R. on 1/26/2024

Kerry W. on 1/31/2024

john d. on 1/31/2024

Erin M. on 2/10/2024

Stacey S. on 2/18/2024

shahid m. on 2/28/2024

Gardenia Z. on 3/7/2024

Tyler J. on 3/10/2024

Malani K. on 3/11/2024

Randall W. on 3/14/2024

Yashma P. on 3/17/2024

Mark K. on 3/17/2024

Maureen H. on 3/18/2024

Kathryn H. on 3/20/2024

Luis P. on 3/21/2024

Yago N. on 3/27/2024

Julie C. on 4/3/2024

Nathan S. on 4/4/2024

Tiffany M. on 4/5/2024

Stacy T. on 4/5/2024

David R. on 4/6/2024

Yashpal m. on 4/7/2024

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