Immunodeficiency

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  Immunodeficiency

Credits: 1.00   Post-Assessment Questions:  2

Release Date: 5 Oct 2020
Expiration Date: 30 Dec 2021
Last Reviewed: 30 Dec 2020
Estimated Time To Finish: 60 Minutes

Need Help?  If you have a system or content concerns, please contact support@statpearls.com, or call (727) 289-9796.

Activity Description

Immunodeficiency results from a failure or absence of elements of the immune system, including lymphocytes, phagocytes, and complement system. Immunodeficiencies can be primary or secondary. Primary immunodeficiency is subdivided into types that cause T-cell deficiency, B-cell deficiency, both T-cell and B-cell deficiency, complement deficiency, phagocyte deficiency, and immunoglobulin A deficiency. Primary immunodeficiencies leading to T-cell deficiency include DiGeorge syndrome, also known as congenital thymic aplasia, chronic mucocutaneous candidiasis, hyper-immunoglobulin M syndrome, and interleukin-12 receptor deficiency. Primary immunodeficiency leading to B-cell deficiency include X-linked agammaglobulinemia, also called Bruton agammaglobulinemia. Primary immunodeficiencies leading to both T-cell and B-cell deficiency include severe combined immunodeficiency disease, Wiskott-Aldrich syndrome, immunodeficiency with ataxia-telangiectasia, and Major Histocompatibility Complex deficiency. Primary immunodeficiencies leading to complement deficiency include hereditary angioedema, deficiency of C3, deficiency of membrane attack complex, and C2 or C4 deficiency secondary to autoimmunity. Primary immunodeficiencies leading to phagocyte deficiency include chronic granulomatous disease and leukocyte adhesion deficiency syndrome. Selective immunoglobulin A deficiency is also a primary immunodeficiency. Secondary causes of immunodeficiency include steroids, nutrient deficiency, obesity, acquired immune deficiency syndrome (AIDS), or other viral infections. This activity reviews the different immunological disorders, their evaluation, and management, and highlights the role of the interprofessional team in caring for affected individuals.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Outline the immunodeficiency disorders.
  • Describe the presentation of a patient with an immunodeficiency disorder.
  • Review the treatment options for immunodeficiency disorders.

Author(s) / Contributors Disclosure of Conflicts of Interest

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Contributors

Hover over the contributor names to see details and disclosures of any financial relationships or relationships they or their spouse/life partner have with commercial interests related to the content of this continuing education activity.

Authors: Angel Justiz Vaillant
Editors: Ahmad Qurie
Editors-In-Chief: Joshua TuckPrashanth AnandMatthew Varacallo
Chief Medical Reviewer: Abhishek Kumar
Nurse Planner/Reviewer/Editor: Lisa Haddad
Nurse Planner/Reviewer/Editor: Bernadette Makar
Nurse Planner/Reviewer/Editor: Dorothy Caputo
Pharmacy Planner/Reviewer/Editor: Mark Pellegrini
Physician Planner/Reviewer/Editor: Scott Dulebohn

Continuing Education Accreditation Information


The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.00 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

 

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

  • If you have content or system concerns, please contact support@statpearls.com, or call 727-289-9796.
  • If you have activity or credit concerns, please contact guy@campbell.edu, or call 910-893-7960.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.

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