Allergic and Drug-Induced Interstitial Nephritis

Overview

4.7 out of 5 (63 Reviews)

Credits

1.00

Post Assessment Questions

5

Start Date

1 Jan 2021

Last Review Date

12 Sep 2023

Expiration Date

31 Dec 2023

Estimated Time To Finish

60 Minutes


 
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Activity Description

Drug-induced acute interstitial nephritis (DI-AIN), also called allergic acute interstitial nephritis, is the most common cause of acute interstitial nephritis (AIN) in developed countries. DI-AIN is associated with a sharp decline in renal function, often requiring dialysis, and has the potential for permanent renal insufficiency, especially if left untreated. Differentiating from other causes of acute kidney injury and discontinuing the causative medication is key to early reversibility. Renal biopsy is the definitive diagnostic test for AIN, and barring chronic changes seen on biopsy or contraindications, steroid therapy is the preferred treatment. This activity discusses the etiology, pathophysiology, clinical symptomatology, and treatment while emphasizing the interprofessional team's role in managing allergic interstitial nephritis.


Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify potential allergic and drug-induced acute interstitial nephritis cases by recognizing varied presentations and conducting a thorough medication history review.

  • Differentiate allergic and drug-induced acute interstitial nephritis from other causes of acute kidney injury through clinical assessment, laboratory investigations, and renal biopsy if indicated.

  • Apply evidence-based guidelines for the treatment of allergic and drug-induced acute interstitial nephritis, including the judicious use of corticosteroids when indicated, weighing the potential benefits against risks.

  • Coordinate care and follow-up for patients with allergic and drug-induced acute interstitial nephritis to monitor renal function, medication adjustments, and potential long-term consequences, aiming for optimal outcomes.

Disclosures

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they or their immediate family may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by CUSOM for resolution, to ensure fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

CUSOM will identify, review, and resolve all conflicts of interest that faculty, authors, activity directors, planners, managers, peer reviewers, or relevant staff disclose prior to an educational activity being delivered to learners. Disclosure of a relationship is not intended to suggest or condone bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation. Disclosure information for authors, editors, planners, peer reviewers, and/or relevant staff is provided with this activity.

Continuing Education Accreditation Information

 

 

The Campbell University Jerry M. Wallace School of Osteopathic Medicine (CUSOM) is accredited by the American Osteopathic Association to provide osteopathic continuing medical education for physicians. CUSOM designates this enduring material for a maximum of 1.00 AOA Category 1 B Credits and will report CME credits commensurate with the extent of the physician's participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money back guarantee is provided if not completely satisfied.

  • StatPearls and CUSOM reserve the right to cancel any course due to unforeseen circumstances. StatPearls and CUSOM will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

  • StatPearls and CUSOM are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

  • Computer Requirements:  Internet Access
  • E-mail Address

Instructions for Credit

  1. Register for the activity and create a StatPearls login.     
  2. Review the required accreditation information:  Target audience, learning objectives and disclosure information.
  3. Complete the entire self-study activity.
  4. Complete the post-test assessments.
  5. Successfully pass the post-test with a minimum score of 100%.
  6. Complete the evaluation form.
  7. Obtain a certificate.

StatPearls and CUSOM adheres to AOA Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and Campbell that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

This course is intended for osteopathic physicians who wish to earn AOA CME credit. Take this version of the course to ensure you receive appropriate credit.

 

 
 

Reviews

Deborah Z. on 2/22/2021

Halyna H. on 6/1/2021

OSCAR P. on 9/13/2021

susma r. on 11/27/2021

Hardy M. on 1/25/2022

patricia h. on 2/1/2022

on 2/22/2022

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Dr.NIRMALA M. on 11/1/2022

Kriti M. on 11/21/2022

Good info

Kenneth R. on 12/7/2022

Meda H. on 1/16/2023

Amy J. on 2/6/2023

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