Cowden Disease

Cowden Disease

Credits: 1.25   Post-Assessment Questions:  10

Release Date: 5 Oct 2020
Expiration Date: 17 Jan 2022
Last Reviewed: 17 Jan 2021
Estimated Time To Finish: 75 Minutes

Need Help?  If you have a system or content concerns, please contact support@statpearls.com, or call (727) 289-9796.

Activity Description

Cowden disease, also known as Cowden syndrome or multiple hamartoma syndrome, is an uncommon autosomal dominant genodermatosis and is a member of the spectrum of disorders involving mutations in the phosphatase and tensin homolog gene. Cowden syndrome represents the most common phenotype associated with this spectrum and it is classically is characterized by multiple benign hamartomas that can occur in any organ. Patients with Cowden syndrome characteristically develop mucocutaneous lesions and macrocephaly. The majority of patients with Cowden syndrome develop a malignant neoplasm of the thyroid, endometrium, or breast. This activity describes the pathophysiology, evaluation, and management of Cowden syndrome and highlights the role of the interprofessional team in the care of affected patients.

Target Audience

This activity has been designed to meet the educational needs of physicians.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

• Describe the pathophysiology of Cowden syndrome.
• Describe the presentation of a patient with Cowden syndrome.
• Describe the utility of routinely screening for malignancy in patients with Cowden syndrome.

Author(s) / Contributors Disclosure of Conflicts of Interest

Each author, editor, faculty and planning committee member have completed a disclosure form indicating that neither they nor their spouse/partner has a financial interest/arrangement or affiliation that could be perceived as a real or apparent conflict of interest related to the content of this activity.

COMMERCIAL SUPPORT: This activity has received NO commercial support.

Contributors

Hover over the contributor names to see details and disclosures of any financial relationships or relationships they or their spouse/life partner have with commercial interests related to the content of this continuing education activity.

Authors: Craig Garofola, Zohaib Jamal
Editors: Gary Gross
Editors-In-Chief: Smita JhaSartaj SandhuVishnu Garla
Chief Medical Reviewer: Muhammad Hashmi
Nurse Planner/Reviewer/Editor: Lisa Haddad
Nurse Planner/Reviewer/Editor: Bernadette Makar
Nurse Planner/Reviewer/Editor: Dorothy Caputo
Pharmacy Planner/Reviewer/Editor: Mark Pellegrini
Physician Planner/Reviewer/Editor: Scott Dulebohn

Continuing Education Accreditation Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Quillen College of Medicine, East Tennessee State University, and StatPearls, LLC. The Quillen College of Medicine, East Tennessee State University is accredited by the ACCME to provide continuing medical education for physicians.

Quillen College of Medicine, East Tennessee State University designates this activity for a maximum of 1.25 AMA PRA Category 1 Credits^TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Cancellation Policy: Cancellations must be received in writing and a money-back guarantee is provided if not completely satisfied.

• StatPearls and ETSU reserve the right to cancel any course due to unforeseen circumstances. StatPearls and ETSU will not be responsible for other expenses incurred by the participant in the unlikely event that the program is canceled.

Equal Opportunity

• StatPearls and ETSU are Equal Opportunity / Affirmative Action / Equal Access Institutions. 

Medium or Media Used:

• Computer Requirements:  Internet Access
• E-mail Address

Instructions for Credit

1. Register for the activity and create a StatPearls login.     
2. Review the required accreditation information:  Target audience, learning objectives, and disclosure information.
3. Complete the entire self-study activity.
4. Complete the post-test assessments.
5. Successfully pass the post-test with a minimum score of 100%.
6. Complete the evaluation form.
7. Obtain a certificate.

StatPearls and ETSU adhere to ACCME Standards regarding commercial support of continuing medical education. It is the policy of StatPearls and ETSU that the faculty and planning committee disclose real or apparent conflicts of interest relating to the topics of this educational activity, that relevant conflict(s) of interest are resolved, and also that authors and editors will disclose any unlabeled/unapproved use of drug(s) or device(s) during their presentation. Detailed disclosure will be made prior to starting the activity.

The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

• If you have concerns, please contact support@statpearls.com, or call 727-289-9796.

Media Usage Rights

The contributors and editors of StatPearls have attested that all associated media (images and video) have been legally cleared for use with this activity.  All copyrights are reserved.