Lipid Emulsion Therapy

Overview

4.5 out of 5 (16 Reviews)

Credits

1.00

Post Assessment Questions

6

Start Date

1 Sep 2023

Last Review Date

16 Feb 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Intravenous lipid emulsion (ILE) therapy, also known as lipid resuscitation therapy, is the established standard treatment for local anesthetic systemic toxicity (LAST), including local anesthetic-mediated cardiac arrest. Professional societies such as the American Society of Regional Anesthesia (ASRA) recommend this therapy in the medical field. Although ILE therapy has been experimentally used to rescue lipophilic drug overdoses and toxicities, outcomes vary. ILE therapy is additionally recommended as an adjunct to advanced cardiac life support measures in cases of suspected LAST-induced cardiac arrest.

ILE therapy extends beyond LAST to encompass other lipophilic agents, emerging as a potential rescue therapy in emergency rooms and critical care units for various acute toxicities and poisonings. The applicability of this therapy extends across numerous multidisciplinary healthcare professions, including physicians, advanced practice practitioners, nursing staff, and pharmacists, particularly those involved in anesthesiology, emergency medicine, medical toxicology, and critical care departments. Despite its growing recognition, further clinical studies are imperative to clarify its mechanism of action, optimal dosing, and the management of associated complications. This activity provides an overview of the indications and contraindications for ILE therapy—an invaluable agent in managing local anesthetic toxicity. This activity allows participating clinicians to acquire insights into the treatment of patients presenting with local anesthetic toxicity and related conditions via ILE therapy.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify appropriate indications for intravenous lipid emulsion therapy based on clinical presentation and local anesthetic systemic toxicity risk factors.

  • Screen patients for contraindications and potential risks associated with intravenous lipid emulsion therapy, considering comorbidities and concurrent medications.

  • Apply knowledge of lipid emulsion therapy in managing acute toxicities beyond local anesthetic systemic toxicity, considering lipophilic drug overdoses and poisonings.

  • Collaborate with multidisciplinary healthcare professionals, including physicians, pharmacists, nurses, and toxicologists, for medication reconciliation and care coordination in complex cases requiring additional expertise in managing drug-related toxicities.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.00 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Dorothy B. on 6/26/2021

Linda R. on 8/7/2021

Cynthia M. on 8/26/2021

Mary S. on 9/14/2021

Annastasia S. on 12/1/2021

Cherie T. on 12/31/2021

OFER R. on 1/5/2022

Lindsay W. on 4/19/2022

Catherine. C. on 5/6/2022

Judith B. on 8/29/2022

William P. on 11/12/2022

Jamie H. on 11/27/2022

Carla B. on 12/7/2022

Marguerite B. on 1/6/2023

Carolyn S. on 3/1/2023

Richard C. on 7/7/2023

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