Most annular fissures are asymptomatic, but some may be painful. Typically, simple symptomatic annular fissures without disc herniation are treated with non-steroidal anti-inflammatory medications and low-impact physical therapy. Chronic pain due to annular fissures can be due to granulation tissue or in-growth of nerve endings which is usually seen near the dorsal root ganglion. Additionally, an annular fissure can allow extrusion, for example, disc herniation, of the nucleus pulposus and compress the adjacent nerves.
The annulus fibrosus is the type I collagen surrounding the nucleus pulposus in approximately 15-20 layers. Together the annulus fibrosis and nucleus pulposus form the intervertebral disc between adjacent vertebrae. The annulus fibrosus runs obliquely between edges of adjacent vertebrae, connecting the inferior endplate of the superior vertebra with the superior endplate of the inferior vertebra. The directions of the layers of the annulus fibrosus alternate which adds to the strength of the annulus fibrosus. Near the central region, the annulus fibrosus blends with the nucleus pulposus. The posterolateral aspect of the annulus fibrosus has a greater content of vertically oriented fibers leading to relative focal weakness at the posterolateral aspect. This anatomy of the annulus fibrosus explains why most annular fissures are at the posterior or posterolateral aspect of the annulus fibrosus.
The posterolateral aspect of the annulus fibrosus has a greater content of vertically oriented collagen fibers. In other regions of the annulus fibrosus layers are alternating obliquely oriented layers. Thus in the postero-lateral region, the vertical alignment of the fibers is more likely to allow for focal deficits of the annulus fibrosus and tearing or separation between the vertically oriented fibers.
Most annular fissures or annular tears are asymptomatic and discovered incidentally on imaging. If an annular fissure or tear is symptomatic, it may cause one of two findings: localized pain secondary to the tear or radicular symptoms secondary to irritation of the passing nerve root. The pain may either be acute if the tear occurs suddenly or more chronic if there is the slower development of the annular fissure.
If the annular fissure is locally symptomatic, it may cause pain localized deep pain worse with movements which can stress or irritate the focal annular tear. In such cases, there is no radicular nerve involvement, and the physical exam may be unrevealing. Sometimes the annular tear can irritate the traversing nerve and cause a radiculopathy. If the annular fissure or annular tear is significant enough, disc material can herniate to irritate or compress traversing nerves or spinal cord. In either case, when the traversing nerve is irritated, it can cause radicular symptoms including pain, paresthesia, and/or weakness depending on the extent of nerve irritation or compromise.
An annular fissure can be concentric, transverse, or radial in orientation and may involve some or all layers. On MRI T2 sequence, the annular fissure is hyper intense (bright) compared to the rest of the annulus fibrosus (which is normally hypointense or dark) due to the relative increase in water content at the fissure compared to the normal annulus fibrosus.
If there is herniation of intravertebral disc material, there must be incompetence of the annulus fibrosus, and thus, an annular fissure or annular tear must be present even if not specifically visualized on the imaging. Thus, an annular fissure or annular tear can be implicated any time intravertebral disc herniation is identified.
If a patient is unable to have an MRI, a CT myelogram may show nerve root or cord compression from a disc protrusion. The CT scan can not identify the edema of an annulus fibrosus tear or fissure and thus, it is less sensitive than MRI.
An annular fissure or tear can be symptomatic or asymptomatic. Symptomatic annular fissures can occur with or without intravertebral disc protrusion or herniation. Each entity is discussed separately below.
Asymptomatic Annular Tear
If the annular tear or fissure is identified incidentally, most commonly on MRI imaging, then no treatment is warranted. Such annular fissures may resolve spontaneously over time and are frequently due to the stresses applied to the spine. It is posited that some asymptomatic annular tears may become symptomatic with time, but there is currently no definitive evidence that treatment of asymptomatic annular tears provides any benefit or prevents any future issues.
Symptomatic Annular Tear without Disc Protrusion or Herniation
An annular fissure or tear can be symptomatic without disc protrusion or herniation. It is suspected that local inflammatory reactions from the annulus fibrosus tear or fissure lead to irritation of adjacent nerve fibers or traversing nerve roots. The mainstay of treatment for such situations is non-steroidal anti-inflammatory medications as well as low-impact physical therapy. The non-steroidal anti-inflammatory medications may help decrease the inflammatory reaction at the annular fissure which decreases stimulation or irritation of adjacent nerve fibers or traversing nerve roots. The low-impact physical therapy may help strength core muscles to mitigate the forces which may have originally led to the annular fissure or tear. Some have suggested local transforaminal steroid injections may alleviate the symptoms more quickly.
Some have argued that long-standing annular fissures or tears may lead to granulation tissue formation at the site of the annulus fibrosus tear or fissure. This local granulation tissue can either irritate or compress the traversing nerve root and lead to a radicular pattern of symptoms. The first-line treatment for such situations is non-steroidal anti-inflammatory medications and low impact physical therapy as discussed above with or without transforaminal steroid injection. In longer-standing cases or instances with weakness or progression some suggest decompression of the nerve with a foraminotomy may prevent further deterioration and improve the symptoms. Some have suggested resecting the granulation tissue itself.
Symptomatic Annular Tear with Disc Protrusion or Herniation
If there is disc protrusion or herniation, it is usually the protruding or herniated disc material itself which causes the clinical symptoms. In such cases, the patient is treated for the disc protrusion or herniation and not the annular fissure or tear. Treatment options for disc protrusion or herniation including conservative measures of nonsteroidal anti-inflammatory medications, physical therapy, and local injections. If symptoms fail to improve, symptoms progress or the patient develops weakness surgical treatment options should be considered including laminotomy, laminectomy, foraminotomy, discectomy, fusion, or some combination thereof. If a discectomy is performed there has been no convincing evidence that closure of the annular fissure, tear, or annulotomy significantly affects the long-term outcome for the patient.
Annular tears are quite common and often associated with low back pain. The diagnosis of annular tear and its correlation to symptoms is not always easy. Many patients with mild annular tears have no symptoms and there are others who present with excruciating low back pain, but with minimal evidence of an annular tear. Thus, a thorough neurological exam is key. The decision to obtain imaging studies depends on the severity of symptoms. However, the treatment of annular tears also requires good clinical judgment. A number of patients do improve with conservative treatment like weight loss, regular exercise, discontinuation of smoking, adopting proper lifting techniques, using safety equipment at work and during sports, and avoiding a sedentary lifestyle.
|||Teraguchi M,Yim R,Cheung JP,Samartzis D, The association of high-intensity zones on MRI and low back pain: a systematic review. Scoliosis and spinal disorders. 2018 [PubMed PMID: 30377668]|
|||Namboothiri S,Gore S,Veerasekhar G, Treatment of Low Back Pain by Treating the Annular High Intensity Zone (HIZ) Lesions Using Percutaneous Transforaminal Endoscopic Disc Surgery. International journal of spine surgery. 2018 Jun [PubMed PMID: 30276096]|
|||Shahraki NM,Fatemi A,Agarwal A,Goel VK, Prediction of clinically relevant initiation and progression of tears within annulus fibrosus. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2017 Jan [PubMed PMID: 27325391]|
|||Simon J,McAuliffe M,Shamim F,Vuong N,Tahaei A, Discogenic low back pain. Physical medicine and rehabilitation clinics of North America. 2014 May [PubMed PMID: 24787335]|
|||Camp CL,Conti MS,Sgroi T,Cammisa FP,Dines JS, Epidemiology, Treatment, and Prevention of Lumbar Spine Injuries in Major League Baseball Players. American journal of orthopedics (Belle Mead, N.J.). 2016 Mar-Apr [PubMed PMID: 26991566]|
|||Stadnik TW,Lee RR,Coen HL,Neirynck EC,Buisseret TS,Osteaux MJ, Annular tears and disk herniation: prevalence and contrast enhancement on MR images in the absence of low back pain or sciatica. Radiology. 1998 Jan [PubMed PMID: 9423651]|
|||Suthar P,Patel R,Mehta C,Patel N, MRI evaluation of lumbar disc degenerative disease. Journal of clinical and diagnostic research : JCDR. 2015 Apr [PubMed PMID: 26023617]|
|||Farshad-Amacker NA,Hughes AP,Aichmair A,Herzog RJ,Farshad M, Is an annular tear a predictor for accelerated disc degeneration? European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2014 Sep [PubMed PMID: 24622958]|
|||Zhou Y,Abdi S, Diagnosis and minimally invasive treatment of lumbar discogenic pain--a review of the literature. The Clinical journal of pain. 2006 Jun [PubMed PMID: 16772802]|